Total AKAP 10 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3465C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • AKAP10
    • Human Swiss Prot No：
    • O43572
    • Mouse Swiss Prot No：
    • O88845
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)
    • Detection Method：
    • Colorimetric
    • Background：
    • domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase.,similarity:Contains 2 RGS domains.,subcellular location:Predominantly mitochondrial but also membrane associated and cytoplasmic.,
    • Function：
    • protein localization,
    • Subcellular Location：
    • Mitochondrion . Membrane . Cytoplasm . Predominantly mitochondrial but also membrane associated and cytoplasmic.

    Attributes

    • Code：
    • KA3465C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-10
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