Total Rit1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3372C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • RIT1
    • Human Gene Id：
    • 6016
    • Human Swiss Prot No：
    • Q92963
    • Mouse Swiss Prot No：
    • P70426
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)
    • Detection Method：
    • Colorimetric
    • Background：
    • enzyme regulation:Alternate between an inactive form bound to GDP and an active form bound to GTP.,function:Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.,miscellaneous:Shows rapid uncatalyzed guanine nucleotide dissociation rates, which are much faster than those of most Ras subfamily members.,miscellaneous:Stimulation of the NGF and EGF receptor signaling pathways results in rapid and prolonged activation.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. Strongly interacts with BRAF, but only weakly with RAF1. BARF and RAF1 association is dependent upon the GTP-bound state. Interacts with RGL3.,tissue specificity:Expressed in many tissues.,
    • Function：
    • intracellular signaling cascade, small GTPase mediated signal transduction,
    • Subcellular Location：
    • Cell membrane.
    • Expression：
    • Expressed in many tissues.

    Attributes

    • Code：
    • KA3372C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-03
    Order

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