Total Melan-A Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3317C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • MLANA
    • Human Gene Id:
    • 2315
    • Human Swiss Prot No:
    • Q16655
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Melanoma antigen recognized by T-cells 1 (MART-1) (Antigen LB39-AA) (Antigen SK29-AA) (Protein Melan-A)
    • Detection Method:
    • Colorimetric
    • Background:
    • tissue specificity:Expression is restricted to melanoma and melanocyte cell lines and retina.,
    • Subcellular Location:
    • Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
    • Expression:
    • Expression is restricted to melanoma and melanocyte cell lines and retina.