Total GCS-β-1 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3285C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- GUCY1B3
- Human Gene Id:
- 2983
- Human Swiss Prot No:
- Q02153
- Mouse Swiss Prot No:
- O54865
- Rat Swiss Prot No:
- P20595
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:GTP = 3',5'-cyclic GMP + diphosphate.,cofactor:Binds 1 or 2 heme groups per heterodimer.,enzyme regulation:Activated by nitric oxide in the presence of magnesium or manganese ions.,miscellaneous:There are two types of guanylate cyclases: soluble forms and membrane-associated receptor forms.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 1 guanylate cyclase domain.,subunit:Heterodimer of an alpha and a beta chain.,
- Function:
- circulatory system process, purine nucleotide metabolic process, purine nucleotide biosynthetic process, cGMP biosynthetic process, intracellular signaling cascade, nitric oxide mediated signal transduction, blood circulation,nucleoside monophosphate metabolic process, nucleoside monophosphate biosynthetic process, nucleotide biosynthetic process, cyclic nucleotide metabolic process, cyclic nucleotide biosynthetic process, nucleobase, nucleoside and nucleotide biosynthetic process, nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process, nitrogen compound biosynthetic process, cGMP metabolic process,
- Subcellular Location:
- Cytoplasm .
- Expression:
- Detected in brain cortex and cerebellum (at protein level).
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