Total CHOP Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3269C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • DDIT3
    • Human Gene Id:
    • 1649
    • Human Swiss Prot No:
    • P35638
    • Mouse Swiss Prot No:
    • P35639
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (Growth arrest and DNA damage-inducible protein GADD153)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:A chromosomal aberration involving DDIT3 is found in a form of malignant myxoid liposarcoma [MIM:126337]. Translocation t(12;16)(q13;p11) with FUS.,function:Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
    • Function:
    • response to reactive oxygen species, response to amphetamine, transcription, transcription, DNA-dependent,regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, response to DNA damage stimulus, response to oxidative stress, ER overload response, ER-nuclear signaling pathway, response to unfolded protein, cell cycle, cell cycle arrest, aging, response to nutrient, mRNA transcription, response to endogenous stimulus,positive regulation of biosynthetic process, response to extracellular stimulus, response to organic substance,response to inorganic substance, response to organic nitrogen, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, positive regulation of gene expression, regulation of cell death, positive regulation of cell death, response to amine stimulus, cellular homeostasis, cell c
    • Subcellular Location:
    • Cytoplasm . Nucleus . Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation. .