Total Fli-1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3263C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • FLI1
    • Human Gene Id:
    • 2313
    • Human Swiss Prot No:
    • Q01543
    • Mouse Swiss Prot No:
    • P26323
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:A chromosomal aberration involving FLI1 is a cause of Ewing sarcoma [MIM:133450]. Translocation t(11;22)(q24;q12) with EWS.,function:Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.,miscellaneous:Located on a fragment of chromosome 11 flanked on the centromeric side by the acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation breakpoint and on the telomeric side by the Ewing- and neuroepithelioma-associated t(11;22) (q24;q12) breakpoint.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,similarity:Contains 1 PNT (pointed) domain.,subunit:Can form homodimers or heterodimers with ETV6/TEL1.,
    • Function:
    • circulatory system process, transcription, regulation of transcription, DNA-dependent, hemostasis, blood circulation,regulation of transcription, regulation of body fluid levels, regulation of RNA metabolic process,
    • Subcellular Location:
    • Nucleus .