Total Cyclin G Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3240C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CCNG1
    • Human Gene Id:
    • 900
    • Human Swiss Prot No:
    • P51959
    • Mouse Swiss Prot No:
    • P51945
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Cyclin-G1 (Cyclin-G)
    • Detection Method:
    • Colorimetric
    • Background:
    • developmental stage:Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.,function:May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.,induction:Activated in breast and prostate cancer cells. Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,subcellular location:DNA replication foci after DNA damage.,tissue specificity:High levels in skeletal muscle, ovary, kidney and colon.,
    • Function:
    • regulation of cyclin-dependent protein kinase activity, M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, cell cycle, mitosis, regulation of cell size, cell growth, regulation of phosphate metabolic process, cell cycle process, cell cycle phase, regulation of cellular component size, growth, regulation of phosphorylation, regulation of kinase activity, regulation of protein kinase activity, organelle fission, regulation of phosphorus metabolic process, cell division, regulation of transferase activity, regulation of cell cycle,
    • Subcellular Location:
    • Nucleus . DNA replication foci after DNA damage.
    • Expression:
    • High levels in skeletal muscle, ovary, kidney and colon.