Total Bak Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3208C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • BAK1
    • Human Gene Id：
    • 578
    • Human Swiss Prot No：
    • Q16611
    • Mouse Swiss Prot No：
    • O08734
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
    • Detection Method：
    • Colorimetric
    • Background：
    • caution:Could be the product of a pseudogene.,domain:Intact BH3 domain is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family. Apoptotic members of the Bcl-2 family.,domain:Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.,function:In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the a repressor Bcl-2 or its adenovirus homolog E1B 19k protein.,function:In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the a. repressor BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.,similarity:Belongs to the Bcl-2 family.,subunit:Forms heterodimers with Bcl-2, E1B 19k protein, and Bcl-X(L).,subunit:Interacts with BCL2A1 (By similarity). Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L).,tissue specificity:Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.,
    • Function：
    • blood vessel development, eye development, cell activation, leukocyte homeostasis, B cell homeostasis, B cell apoptosis, release of cytochrome c from mitochondria, regulation of protein amino acid phosphorylation, negative regulation of protein amino acid phosphorylation, vasculature development, blood vessel remodeling, lymphocyte homeostasis, myeloid cell homeostasis, B cell selection, B cell negative selection, immune system development,leukocyte differentiation, reproductive developmental process, mitochondrial transport, cellular ion homeostasis,cellular calcium ion homeostasis, cellular metal ion homeostasis, apoptosis, induction of apoptosis, activation of caspase activity, membrane fusion, mitochondrion organization, mitochondrial membrane organization, sensory organ development, mitochondrial fusion, cell death, cell proliferation, activation of caspase activity by cytochrome c,
    • Subcellular Location：
    • Mitochondrion outer membrane ; Single-pass membrane protein .
    • Expression：
    • Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.

    Attributes

    • Code：
    • KA3208C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-03
    Order

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