• 靶点：
• Smad1/5/9

• 简介：
• >>TGF-beta signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Transcriptional misregulation in cancer

• 基因名称：
• SMAD1/SMAD5/SMAD9

• 蛋白名称：
• Mothers against decapentaplegic homolog 1/Mothers against decapentaplegic homolog 5/Mothers against decapentaplegic homolog 9

• Human Gene Id：
• 4086/4090/4093

• Human Swiss Prot No：
• Q15797/Q99717/O15198

• Mouse Gene Id：
• 17125/17129/55994

• Rat Gene Id：
• 59328/85435

• Rat Swiss Prot No：
• P97588/Q9R1V3/O54835

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Smad1/5/9. AA range:10-59

• 特异性：
• Smad1/5/9 Polyclonal Antibody detects endogenous levels of Smad1/5/9 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SMAD1;BSP1;MADH1;MADR1;Mothers against decapentaplegic homolog 1;MAD homolog 1;Mothers against DPP homolog 1;JV4-1;Mad-related protein 1;SMAD family member 1;SMAD 1;Smad1;hSMAD1;Transforming growth factor-beta-signaling protein

• 实测条带：
• 56kD

• 背景：
• The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med

• 功能：
• function:Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).,PTM:Phosphorylated on serine by BMP type 1 receptor kinase.,PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.,similarity:Belongs to the dwarfin/SMAD family.,similarity:Contains 1 MH1 (MAD homology 1) domain.,similarity:Contains 1 MH2 (MAD homology 2) domain.,subcellular location:Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.,subunit:Interacts with HGS, NANOG and ZCCHC12 (By similarity). May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), p300, SMURF1, SMURF2 and HOXC8. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with LBXCOR1.,

• 细胞定位：
• Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271). Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity). .

• 组织表达：
• Ubiquitous. Highest expression seen in the heart and skeletal muscle.

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Changes in the Gut Microbiome Contribute to the Development of Behcet’s Disease via Adjuvant Effects. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Sep;0:2482 WB Mouse 1:1000 Colon
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Changes in the Gut Microbiome Contribute to the Development of Behcet’s Disease via Adjuvant Effects. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Sep;0:2482 IF Mouse Neutrophils
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Changes in the Gut Microbiome Contribute to the Development of Behcet’s Disease via Adjuvant Effects. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Sep;0:2482 IF Mouse Neutrophils
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Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021; 9: 687024 WB Human，Mouse，Rat 1:1000 Nucleus pulposus （NP）tissues
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Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021; 9: 687024 WB Human，Mouse，Rat 1:1000 Nucleus pulposus （NP）tissues
货号：YT4325

GADD45B Is a Potential Diagnostic and Therapeutic Target Gene in Chemotherapy-Resistant Prostate Cancer. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021; 9: 716501 IHC，WB Human 1:100，1:500 Prostate cancer (PCa) tissue
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The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 May;0:1268 WB Mouse 1 : 200 Retina BV2 cell
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Cholesterol Induces Pyroptosis and Matrix Degradation via mSREBP1-Driven Endoplasmic Reticulum Stress in Intervertebral Disc Degeneration.. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Jan;9:803132-803132 IF Rat 1:100 Nucleus pulposus (NP) cell
货号：YT4325

A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Jan;9:774625-774625 IHC Human Prostate cancer (PCa) tissue，benign prostatic hyperplasia (BPH) tissue
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CircINSR Regulates Fetal Bovine Muscle and Fat Development. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2020; 8: 615638 IF Bovine 1:500 Myoblasts
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Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2020 Dec;8:1562 WB Human RPMI8226 cell，MM1.S cell
货号：YT4325

Mechanism of deoxynivalenol-induced neurotoxicity in weaned piglets is linked to lipid peroxidation, dampened neurotransmitter levels, and interference with calcium signaling. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY Ecotox Environ Safe. 2020 May;194:110382 WB Pig Brain
货号：YT4325

Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion. EBioMedicine 2019 Oct 05 WB Rat cardiac
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Hepatitis B Virus X Protein (HBx) Suppresses Transcription Factor EB (TFEB) Resulting in Stabilization of Integrin Beta 1 (ITGB1) in Hepatocellular Carcinoma Cells. Cancers Cancers. 2021 Jan;13(5):1181 WB Human HepG2 cell，SK-Hep-1 cell，HEK-293FT cell
货号：YT4325

Hepatitis B Virus X Protein (HBx) Suppresses Transcription Factor EB (TFEB) Resulting in Stabilization of Integrin Beta 1 (ITGB1) in Hepatocellular Carcinoma Cells. Cancers Cancers. 2021 Jan;13(5):1181 WB Human HepG2 cell，SK-Hep-1 cell，HEK-293FT cell
货号：YT4325

Pilot Study of the Biological Properties and Vascularization of 3D Printed Bilayer Skin Grafts. International Journal of Bioprinting 2020; 6(1): 246 IHC Mouse 1: 500 skin
货号：YT4325

Pilot Study of the Biological Properties and Vascularization of 3D Printed Bilayer Skin Grafts. International Journal of Bioprinting 2020; 6(1): 246 IHC Mouse 1: 500 skin
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Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells Cells-Basel. 2021 Oct;10(10):2647 WB Mouse 1:1000 Cerebral cortices
货号：YT4325

Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells Cells-Basel. 2021 Oct;10(10):2647 WB Mouse 1:1000 Cerebral cortices
货号：YT4325

Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells Cells-Basel. 2021 Oct;10(10):2647 WB Mouse 1:1000 Cerebral cortices
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Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells Cells-Basel. 2021 Oct;10(10):2647 WB Mouse 1:1000 Cerebral cortices
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Circular RNA circMYL1 Inhibit Proliferation and Promote Differentiation of Myoblasts by Sponging miR-2400. Cells Cells-Basel. 2021 Jan;10(1):176 IF Bovine 1: 500 Myoblasts
货号：YT4325

C. tropicalis promotes chemotherapy resistance in colon cancer through increasing lactate production to regulate the mismatch repair system. International Journal of Biological Sciences Int J Biol Sci. 2021; 17(11): 2756–2769 WB Mouse SW480 cell-xenograft
货号：YT4325

MicroRNA-370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis. International Journal of Biological Sciences Int J Biol Sci. 2021; 17(7): 1795–1807 WB Mouse Lung
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Endogenous hydrogen sulfide alleviates methotrexate‐induced cognitive impairment by attenuating endoplasmic reticulum stress‐induced apoptosis via CHOP and caspase‐12. FUNDAMENTAL & CLINICAL PHARMACOLOGY Fund Clin Pharmacol. 2020 Oct;34(5):559-570 IHC Rat 1 : 100 hippocampus
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MiR-487a Promotes TGF-β1-induced EMT, the Migration and Invasion of Breast Cancer Cells by Directly Targeting MAGI2. International Journal of Biological Sciences Int J Biol Sci. 2016; 12(4): 397–408 WB Human 1:1000 MCF-7 cell, MDA-MB-231 cell
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Design and application of hydrophilic bimetallic metal-organic framework magnetic nanoparticles for rapid capture of exosomes. ANALYTICA CHIMICA ACTA Anal Chim Acta. 2021 Nov;1186:339099 WB Human Urinary exosomes HeLa cells
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Design and application of hydrophilic bimetallic metal-organic framework magnetic nanoparticles for rapid capture of exosomes. ANALYTICA CHIMICA ACTA Anal Chim Acta. 2021 Nov;1186:339099 WB Human Urinary exosomes HeLa cells
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Design and application of hydrophilic bimetallic metal-organic framework magnetic nanoparticles for rapid capture of exosomes. ANALYTICA CHIMICA ACTA Anal Chim Acta. 2021 Nov;1186:339099 WB Human Urinary exosomes HeLa cells
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Design and application of hydrophilic bimetallic metal-organic framework magnetic nanoparticles for rapid capture of exosomes. ANALYTICA CHIMICA ACTA Anal Chim Acta. 2021 Nov;1186:339099 WB Human Urinary exosomes HeLa cells
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Protective effect of thioredoxin reductase 1 in Parkinson's disease. NEUROSCIENCE LETTERS Neurosci Lett. 2021 Jan;741:135457 IHC,IF Mouse Brain
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Sustained high expression of NRF2 and its target genes induces dysregulation of cellular proliferation and apoptosis is associated with arsenite-induced malignant transformation of human bronchial epithelial cells. SCIENCE OF THE TOTAL ENVIRONMENT Sci Total Environ. 2021 Feb;756:143840 WB Human Human bronchial epithelial(HBE)
货号：YT4325

Akt inhibition-dependent downregulation of the Wnt/β-Catenin Signaling pathway contributes to antimony-induced neurotoxicity. SCIENCE OF THE TOTAL ENVIRONMENT Sci Total Environ. 2020 Oct;737:140252 IHC Mouse 1:400 Brain
货号：YT4325

Ficus pandurata Hance Inhibits Ulcerative Colitis and Colitis-Associated Secondary Liver Damage of Mice by Enhancing Antioxidation Activity. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:2617881 WB Mouse Colon
货号：YT4325

miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes. INTERNATIONAL JOURNAL OF ONCOLOGY 2016 Nov 01 WB Human SKM-1 cell
货号：YT4325

Pb induced mitochondrial fission of fibroblast cells via ATM activation. JOURNAL OF HAZARDOUS MATERIALS J Hazard Mater. 2021 Aug;416:126177 WB Human 1 : 1000 GM00637 cell
货号：YT4325

Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission. NEUROCHEMICAL RESEARCH Neurochem Res. 2019 Feb;44(2):472-484 WB Mouse 1:500 hippocampus
货号：YT4325

Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:3830671 IF,WB Human 1:1000 HepG2 cells
货号：YT4325

Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:3830671 IF,WB Human 1:1000 HepG2 cells
货号：YT4325

TXNRD1: A Key Regulator Involved in the Ferroptosis of CML Cells Induced by Cysteine Depletion In Vitro. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:7674565 WB Human K562 cell
货号：YT4325

The Antitriple Negative Breast cancer Efficacy of Spatholobus suberectus Dunn on ROS-Induced Noncanonical Inflammasome Pyroptotic Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:5187569 WB Human MDA-MB-231 cells
货号：YT4325

Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:8520967 WB Mouse 1:2000 Hippocampus
货号：YT4325

Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:6693921 WB Fish 1:10000 Neutrophils
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Effects of Fluorine on Neutrophil Extracellular Trap Formation through Regulating AMPK/p38 Signaling Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:6693921 WB Fish 1:10000 Neutrophils
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Mangiferin improves hepatic damage-associated molecular patterns, lipid metabolic disorder and mitochondrial dysfunction in alcohol hepatitis rats. Food & Function Food Funct. 2019 Jun;10(6):3514-3534 IHC Rat Liver, kidney , spleen
货号：YT4325

Bu Shen Yi Sui Capsule Alleviates Neuroinflammation and Demyelination by Promoting Microglia toward M2 Polarization, Which Correlates with Changes in miR-124 and miR-155 in Experimental Autoimmune Encephalomyelitis. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:5521503 WB Mouse 1 : 1000 Myocardium
货号：YT4325

Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:6610124 IF Human LO2 cell
货号：YT4325

Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2021;2021:6610124 WB，IP Human Liver LO2 cell
货号：YT4325

CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions. MOLECULAR CARCINOGENESIS Mol Carcinogen. 2017 Oct;56(10):2245-2257 WB Human,Mouse 1:1000 CaSki cell-xenograft,cervical cancer tissues CaSki cell， HeLa cell
货号：YT4325

Inhibition of store‑operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncology Letters Oncol Lett. 2017 Feb;13(2):921-929 WB Human 5–8F cell,6–10B cell
货号：YT4325

Hydroxy-α-sanshool Possesses Protective Potentials on H2O2-Stimulated PC12 Cells by Suppression of Oxidative Stress-Induced Apoptosis through Regulation of PI3K/Akt Signal Pathway. Oxidative Medicine and Cellular Longevity Oxid Med Cell Longev. 2020;2020:3481758 WB Rat 1 : 1000 PC12 cell
货号：YT4325

Protective effects of a novel probiotic strain, Lactococcus lactis ML2018, in colitis: in vivo and in vitro evidence. Food & Function Food Funct. 2019 Feb;10(2):1132-1145 WB Mouse 1:50 colon tissues
货号：YT4325

Preventive effect of sanguinarine on intestinal injury in mice exposed to whole abdominal irradiation. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2022 Feb;146:112496 WB Rat IEC-6 cell
货号：YT4325

Structural characterization of a water-soluble polysaccharide from Angelica dahurica and its antitumor activity in H22 tumor-bearing mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Int J Biol Macromol. 2021 Dec;193:219 FC Mouse Peripheral blood
货号：YT4325

Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration. JOURNAL OF NANOBIOTECHNOLOGY J Nanobiotechnol. 2021 Dec;19(1):1-16 IF Human 1:200 hBMSCs
货号：YT4325

Cajanolactone A, a stilbenoid from Cajanus cajan, inhibits energy intake and lipid synthesis/storage, and promotes energy expenditure in ovariectomized mice. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2021 Jun;138:111491 WB Mouse 1:10000 Hypothalami, BATs, iWATs, pWATs, liver
货号：YT4325

Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2021 Jun;138:111403 WB Mouse 1:1000 Lung
货号：YT4325

Gu-Ben-Fang-Xiao decoction modulates lipid metabolism by activating the AMPK pathway in asthma remission. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2021 Jun;138:111403 WB Mouse 1:1000 Lung
货号：YT4325

Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle. ACS Applied Materials & Interfaces Acs Appl Mater Inter. 2019;11(43):39545–39559 IF Mouse 1:100 4T1 tumor
货号：YT4325

Rg1 Attenuates alcoholic hepatic damage through regulating AMP-activated protein kinase and nuclear factor erythroid 2-related factor 2 signal pathways. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 2016 May 26 WB Mouse liver
货号：YT4325

PTH1-34 promotes osteoblast formation through Beclin1-dependent autophagic activation. JOURNAL OF BONE AND MINERAL METABOLISM J Bone Miner Metab. 2021 Jul;39(4):572-582 WB Mouse MC3T3-E1 cell
货号：YT4325

Structural characterization of a water-soluble polysaccharide from Angelica dahurica and its antitumor activity in H22 tumor-bearing mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Int J Biol Macromol. 2021 Dec;193:219 FC Mouse Peripheral blood
货号：YT4325

Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G 2 /M phase arrest via the p38 MAPK signaling pathway. ACTA PHARMACOLOGICA SINICA Acta Pharmacol Sin. 2014 Sep;35(10):1311-1322 WB Human HepG2 cell
货号：YT4325

CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions. MOLECULAR CARCINOGENESIS Mol Carcinogen. 2017 Oct;56(10):2245-2257 WB Human,Mouse 1:1000 CaSki cell-xenograft,cervical cancer tissues CaSki cell， HeLa cell
货号：YT4325

Paclitaxel increases sensitivity of SKOV3 cells to hyperthermia by inhibiting heat shock protein 27. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2020 Dec;132:110907 WB Human SKOV3 cell
货号：YT4325

Gu-Ben-Fang-Xiao attenuates allergic airway inflammation by inhibiting BAFF-mediated B cell activation. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2020 Dec;132:110801 WB Mouse 1 : 1000 Lung，spleen
货号：YT4325

Down-regulation of FoxM1 by thiostrepton or small interfering RNA inhibits proliferation, transformation ability and angiogenesis, and induces apoptosis of nasopharyngeal carcinoma cells. International Journal of Clinical and Experimental Pathology Int J Clin Exp Patho. 2014; 7(9): 5450–5460 WB Human Nasopharyngeal carcinoma (NPC) cell
货号：YT4325

α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis. Frontiers in Cell and Developmental Biology Front Cell Dev Biol. 2021 Aug;0:2161 IHC Mouse Aortic root
货号：YT4325

Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Int J Mol Sci. 2021 Jan;22(19):10229 WB Rat Renal tissues NRK-52E cell
货号：YT4325

Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2019 Nov;119:109390 WB Mouse 1:1000 lung tissue
货号：YT4325

miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes. INTERNATIONAL JOURNAL OF ONCOLOGY 2016 Nov 01 WB Human SKM-1 cell
货号：YT4325

Danggui-Shaoyao-San (DSS) Ameliorates Cerebral Ischemia-Reperfusion Injury via Activating SIRT1 Signaling and Inhibiting NADPH Oxidases. Frontiers in Pharmacology Front Pharmacol. 2021 Apr;0:747 IHC Rat 1 : 100 Brain
货号：YT4325

Rce1 expression in renal cell carcinoma and its regulatory effect on 786-O cell apoptosis through endoplasmic reticulum stress. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 2017 Mar 01 WB Human 1:2000 renal cancer tissues 786-O cell
货号：YT4325

Insulin regulates primordial-follicle assembly in vitro by affecting germ-cell apoptosis and elevating oestrogen. REPRODUCTION FERTILITY AND DEVELOPMENT Reprod Fert Develop. 2015 Oct;27(8):1197-1204 WB Mouse ovaries
货号：YT4325

CXCL5, the upregulated chemokine in patients with uterine cervix cancer, in vivo and in vitro contributes to oncogenic potential of Hela uterine cervix cancer cells. BIOMEDICINE & PHARMACOTHERAPY Biomed Pharmacother. 2018 Nov;107:1496 WB Human,Mouse 1:1000 Hela cell-xenografts Hela cell
货号：YT4325

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation. JOURNAL OF NANOBIOTECHNOLOGY J Nanobiotechnol. 2020 Dec;18(1):1-15 WB,IF,IHC Mouse，Human lung BEAS-2b cell
货号：YT4325

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation. JOURNAL OF NANOBIOTECHNOLOGY J Nanobiotechnol. 2020 Dec;18(1):1-15 WB,IF,IHC Mouse,Human lung BEAS-2b cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 ELISA Mouse Plasma
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB,IHC Human 1:2000,1:250 Breast cancer tissues Cal51 cell, MDA-MB-231 cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB Human 1:2000 Cal51 cell, MDA-MB-231 cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB Human 1:1000 Cal51 cell, MDA-MB-231 cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB Human 1:1000 Cal51 cell, MDA-MB-231 cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB,IHC Human 1:2000，1：250 Breast cancer tissues Cal51 cell, MDA-MB-231 cell
货号：YT4325

Centromere protein U (CENPU) enhances angiogenesis in triple-negative breast cancer by inhibiting ubiquitin–proteasomal degradation of COX-2. CANCER LETTERS 2019 Nov 06 WB Human 1:1000，1：300 Breast cancer tissues Cal51 cell, MDA-MB-231 cell
货号：YT4325

SERPINE2 promotes esophageal squamous cell carcinoma metastasis by activating BMP4. CANCER LETTERS Cancer Lett. 2020 Jan;469:390 WB Human KYSE30 cell, KYSE450 cell
货号：YT4325

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