• 基因名称：
• SMAD1/5/9

• Human Swiss Prot No：
• Q15797/Q99717/O15198

• 储存：
• 2-8°C/6 months

• 检测方法：
• Colorimetric

• 功能：
• MAPKKK cascade, skeletal system development, ossification, osteoblast differentiation, urogenital system development, formation of primary germ layer, mesoderm formation, mesodermal cell fate commitment, kidney development, osteoblast fate commitment, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, RNA processing, protein complex assembly, defense response,inflammatory response, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway, SMAD protein complex assembly, intracellular signaling cascade, protein kinase cascade, gamete generation, gastrulation, pattern specification process, mesoderm development, negative regulation of cell proliferat

• 细胞定位：
• Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271). Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity). .

• 组织表达：
• Ubiquitous. Highest expression seen in the heart and skeletal muscle.

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