Rak Polyclonal Antibody

    • 货号:YT3996
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Rak
      • 基因名称:
      • FRK
      • 蛋白名称:
      • Tyrosine-protein kinase FRK
      • Human Gene Id:
      • 2444
      • Human Swiss Prot No:
      • P42685
      • Mouse Swiss Prot No:
      • Q922K9
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human FRK. AA range:71-120
      • 特异性:
      • Rak Polyclonal Antibody detects endogenous levels of Rak protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • FRK;PTK5;RAK;Tyrosine-protein kinase FRK;FYN-related kinase;Nuclear tyrosine protein kinase RAK;Protein-tyrosine kinase 5
      • 实测条带:
      • 55kD
      • 背景:
      • The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],
      • 功能:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,
      • 细胞定位:
      • Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.
      • 组织表达:
      • Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
      • 产品图片
      • Western Blot analysis of various cells using Rak Polyclonal Antibody
      • Immunofluorescence analysis of HUVEC cells, using FRK Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FRK Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from Jurkat cells, using FRK Antibody. The lane on the right is blocked with the synthesized peptide.