• 靶点：
• Rak

• 基因名称：
• FRK

• 蛋白名称：
• Tyrosine-protein kinase FRK

• Human Gene Id：
• 2444

• Human Swiss Prot No：
• P42685

• Mouse Swiss Prot No：
• Q922K9

• 免疫原：
• Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli.

• 特异性：
• Rak Monoclonal Antibody detects endogenous levels of Rak protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Monoclonal, Mouse

• 稀释：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• Affinity purification

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• FRK;PTK5;RAK;Tyrosine-protein kinase FRK;FYN-related kinase;Nuclear tyrosine protein kinase RAK;Protein-tyrosine kinase 5

• 分子量：
• 58kD

• 背景：
• The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,

• 细胞定位：
• Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.

• 组织表达：
• Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.

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