• Target：
• TIMP-4

• Gene Name：
• TIMP4

• Protein Name：
• Metalloproteinase inhibitor 4

• Human Gene Id：
• 7079

• Human Swiss Prot No：
• Q99727

• Mouse Gene Id：
• 110595

• Mouse Swiss Prot No：
• Q9JHB3

• Rat Gene Id：
• 680130

• Rat Swiss Prot No：
• P81556

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TIMP4. AA range:175-224

• Specificity：
• TIMP-4 Polyclonal Antibody detects endogenous levels of TIMP-4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TIMP4;Metalloproteinase inhibitor 4;Tissue inhibitor of metalloproteinases 4;TIMP-4

• Observed Band(KD)：
• 26kD

• Background：
• This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008],

• Function：
• function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,tissue specificity:Abundant in heart and present at low levels in many other tissues.,

• Subcellular Location：
• Secreted.

• Expression：
• Abundant in heart and present at low levels in many other tissues.

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