• Target：
• RFA2

• Fields：
• >>DNA replication;>>Nucleotide excision repair;>>Mismatch repair;>>Homologous recombination;>>Fanconi anemia pathway

• Gene Name：
• RPA2 REPA2 RPA32 RPA34

• Protein Name：
• RPA32/RPA2 (Ser8)

• Human Gene Id：
• 6118

• Human Swiss Prot No：
• P15927

• Mouse Swiss Prot No：
• Q62193

• Rat Gene Id：
• 59102

• Rat Swiss Prot No：
• Q63528

• Immunogen：
• Synthesized phosho peptide around human RPA32 and RPA2 (Ser8)

• Specificity：
• This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:1000-2000

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)

• Observed Band(KD)：
• 32kD

• Function：
• function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,

• Subcellular Location：
• Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .

• Expression：
• Kidney,Lung,Muscle,

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