β-actin Monoclonal Antibody(5B7), Biotin Conjugated

  • Catalog No.:YM2192
  • Applications:IF/ICC,WB,IHC-p
  • Reactivity:Human,Rat,Mouse,Mk,Dg,Ch,Hamster,Rb,Insect
    • Gene Name:
    • ACTB
    • Protein Name:
    • Actin cytoplasmic 1
    • Human Gene Id:
    • 60
    • Human Swiss Prot No:
    • P60709
    • Specificity:
    • β-actin Monoclonal Antibody(5B7) Biotin conjugated specially designed for your WB or IHC analysis.
    • Formulation:
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • Source:
    • Mouse IgG1
    • Dilution:
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:5000, IHC: 1:200.
    • Purification:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1mg/ml
    • Storage Stability:
    • Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and th
    • Other Name:
    • ACTB
    • Background:
    • actin beta(ACTB) Homo sapiens This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],
    • Function:
    • disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the
    • Subcellular Location:
    • nuclear chromatin,extracellular space,nucleoplasm,cytoplasm,cytosol,cytoskeleton,plasma membrane,focal adhesion,membrane,intracellular ribonucleoprotein complex,cortical cytoskeleton,NuA4 histone acetyltransferase complex,cyt
    • Expression:
    • B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car