• Target：
• CD185

• Gene Name：
• CXCR5 BLR1 MDR15

• Protein Name：
• C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1) (Monocyte-derived receptor 15) (MDR-15) (CD antigen CD185)

• Human Gene Id：
• 643

• Human Swiss Prot No：
• P32302

• Immunogen：
• Purified recombinant Human CD185

• Specificity：
• This recombinant monoclonal antibody can detects endogenous levels of CD185 protein.

• Formulation：
• Phosphate-buffered solution

• Source：
• Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell

• Dilution：
• ELISA 1:5000-100000;FCM 1-2μg/Test

• Purification：
• Recombinant Expression and Affinity purified

• Concentration：
• Please check the information on the tube

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Other Name：
• BLR1;MDR15;BLR 1 antibody;BLR1 antibody;Burkitt lymphoma receptor 1 antibody;Burkitt lymphoma receptor 1 GTP binding protein antibody;Burkitt lymphoma receptor 1;GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody;C X C chemokine receptor type 5 antibody;C-X-C chemokine receptor type 5 antibody;CD 185 antibody;CD185 antibody;CD185 antigen antibody;Chemokine (C-X-C motif) receptor 5 antibody;Chemokine C X C motif receptor 5 antibody;Chemokine CXC motif receptor 5 antibody;Chemokine receptor 5 antibody;CXC chemokine receptor type 5 antibody;CXC R5 antibody;CXC-R5 antibody;CXCR 5 antibody;CXCR-5 antibody;Cxcr5 antibody;CXCR5_HUMAN antibody;MDR 15 antibody;MDR-15 antibody;MDR15 antibody;MGC117347 antibody;Monocyte derived receptor 15 antibody;Monocyte-derived receptor 15 antibody;

• Background：
• CD185, also known as CXCR5, is a 42 kD G-protein coupled receptor with seven transmembrane regions. CXCR5 is expressed by mature B cells, follicular helper T cells, Burkitt’s lymphoma cells and a subset of neurons, and mediates cell migration to the B cell follicles in the secondary lymphoid organs. The ligand of CXCR5 is CXCL13 (BLC).

• Function：
• Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Expression in mature B-cells and Burkitt lymphoma cells.

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