IL-2 (PN0174) Nb-FC recombinant antibody

  • Catalog No.：YA0619
  • Applications：ELISA
  • Reactivity：Human
    • Target：
    • IL-2
    • Gene Name：
    • IL2
    • Protein Name：
    • Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
    • Human Gene Id：
    • 3558
    • Human Swiss Prot No：
    • P60568
    • Immunogen：
    • Purified recombinant Human IL-2
    • Specificity：
    • This recombinant monoclonal antibody can detects endogenous levels of IL-2 protein.
    • Formulation：
    • Phosphate-buffered solution
    • Source：
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution：
    • ELISA 1:5000-100000
    • Purification：
    • Recombinant Expression and Affinity purified
    • Concentration：
    • Please check the information on the tube
    • Storage Stability：
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name：
    • IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin;IL-2 nanobody;
    • Background：
    • The protein encoded byThis gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor ofThis cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression ofThis gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role ofThis gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]
    • Function：
    • disease:A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.,Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,online information:Interleukin-2 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Proleukin (Chiron). Used in patients with renal cell carcinoma or metastatic melanoma.,similarity:Belongs to the IL-2 family.,
    • Subcellular Location：
    • Secreted.
    • Expression：
    • Blood,PCR rescued clones,Placenta,Spleen

    Attributes

    • Code：
    • YA0619
    • Size
    • 40μg / 100μg / 200μg
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-06-26
    Order

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