CD73 (PN0522) Nb-FC recombinant antibody
- Catalog No.:YA0498
- Applications:ELISA
- Reactivity:Human
- Target:
- CD73
- Gene Name:
- NT5E NT5 NTE
- Protein Name:
- 5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)
- Human Gene Id:
- 4907
- Human Swiss Prot No:
- P21589
- Immunogen:
- Purified recombinant Human CD73
- Specificity:
- This recombinant monoclonal antibody can detects endogenous levels of CD73 protein.
- Formulation:
- Phosphate-buffered solution
- Source:
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- Dilution:
- ELISA 1:5000-100000
- Purification:
- Recombinant Expression and Affinity purified
- Concentration:
- Please check the information on the tube
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- NT5E;NT5;NTE;5'-nucleotidase;5'-NT;Ecto-5'-nucleotidase;CD antigen CD73;CD73 nanobody;
- Background:
- The protein encoded byThis gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects inThis gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found forThis gene.[provided by RefSeq, Mar 2011]
- Function:
- catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Zinc.,disease:There is a decrease in the activity of NT5 in B-cell chronic lymphocytic leukemia.,Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.,similarity:Belongs to the 5'-nucleotidase family.,subunit:Homodimer; disulfide-linked.,
- Subcellular Location:
- Cell membrane ; Lipid-anchor, GPI-anchor .
- Expression:
- Leukocyte,Liver,Placenta,Skin
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