CD70 (PN0442) Nb-FC recombinant antibody
- Catalog No.:YA0471
- Applications:ELISA;FCM
- Reactivity:Human
- Target:
- CD70
- Gene Name:
- CD70 CD27L CD27LG TNFSF7
- Protein Name:
- CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)
- Human Gene Id:
- 970
- Human Swiss Prot No:
- P32970
- Immunogen:
- Purified recombinant Human CD70
- Specificity:
- This recombinant monoclonal antibody can detects endogenous levels of CD70 protein.
- Formulation:
- Phosphate-buffered solution
- Source:
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- Dilution:
- ELISA 1:5000-100000;FCM 1-2μg/Test
- Purification:
- Recombinant Expression and Affinity purified
- Concentration:
- Please check the information on the tube
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- CD70;CD27L;CD27LG;TNFSF7;CD70 antigen;CD27 ligand;CD27-L;Tumor necrosis factor ligand superfamily member 7;CD antigen CD70;CD70 nanobody;
- Background:
- The protein encoded byThis gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation.This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
- Function:
- Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,
- Subcellular Location:
- Membrane ; Single-pass type II membrane protein .
- Expression:
- B-cell,Kidney
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