Total TNFC Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA4346C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- TNFC
- Human Gene Id:
- 4050
- Human Swiss Prot No:
- Q06643
- Mouse Swiss Prot No:
- P41155
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3)
- Detection Method:
- Colorimetric
- Background:
- function:Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.,similarity:Belongs to the tumor necrosis factor family.,subunit:Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.,tissue specificity:Spleen and thymus.,
- Function:
- cell activation, regulation of cytokine production, regulation of L-glutamate transport, negative regulation of L-glutamate transport, immune system development, apoptosis, induction of apoptosis, immune response, regulation of mitosis, intracellular signaling cascade, cell-cell signaling, regulation of mitotic cell cycle, ectoderm development, cell death, negative regulation of cell proliferation, epidermis development, response to mechanical stimulus, response to abiotic stimulus, positive regulation of biosynthetic process, positive regulation of signal transduction, positive regulation of macromolecule biosynthetic process, regulation of cell cycle process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of organelle organization, positive regulation of cell communication, positive regulation of protein kinase cascade,
- Subcellular Location:
- Membrane ; Single-pass type II membrane protein .
- Expression:
- Spleen and thymus.
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