Total VE-Cadherin Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4320C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • CDH5
    • Human Gene Id:
    • 1003
    • Human Swiss Prot No:
    • P33151
    • Mouse Swiss Prot No:
    • P55284
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
    • Function:
    • blood vessel development, vasculature development, blood vessel maturation, cell adhesion, homophilic cell adhesion,negative regulation of cell proliferation, cell-cell adhesion, developmental maturation, biological adhesion, regulation of cell proliferation,
    • Subcellular Location:
    • Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. .
    • Expression:
    • Endothelial tissues and brain.