Total Synapsin1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4297C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • SYN1
    • Human Gene Id：
    • 6853
    • Human Swiss Prot No：
    • P17600
    • Mouse Swiss Prot No：
    • O88935
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Synapsin-1 (Brain protein 4.1) (Synapsin I)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.,function:Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.,PTM:Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the synapsin family.,subunit:Homodimer. Interacts with CAPON. Forms a ternary complex with NOS1. Isoform Ib interacts with PRNP.,
    • Function：
    • regulation of neurotransmitter levels, generation of a signal involved in cell-cell signaling, neurotransmitter transport,cell-cell signaling, synaptic transmission, neurotransmitter secretion, transmission of nerve impulse, secretion by cell,secretion, neurological system process,
    • Subcellular Location：
    • Cell junction, synapse. Golgi apparatus .

    Attributes

    • Code：
    • KA4297C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-05-18
    Order

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