Total SSB Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4290C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • SSB
    • Human Gene Id:
    • 6741
    • Human Swiss Prot No:
    • P05455
    • Mouse Swiss Prot No:
    • P32067
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.,function:La protein plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs.,PTM:Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.,PTM:The N-terminus is blocked.,similarity:Contains 1 HTH La-type RNA-binding domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with DDX15. May interact with RUFY1.,
    • Function:
    • RNA processing, tRNA metabolic process, tRNA modification, tRNA processing, histone mRNA metabolic process, RNA modification, mRNA metabolic process, ncRNA processing, ncRNA metabolic process,
    • Subcellular Location:
    • Nucleus .