Total OXSR1 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA4207C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- OXSR1
- Human Gene Id:
- 9943
- Human Swiss Prot No:
- O95747
- Mouse Swiss Prot No:
- Q6P9R2
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined.,
- Function:
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, response to oxidative stress, intracellular signaling cascade, protein kinase cascade, phosphorylation,
- Subcellular Location:
- Cytoplasm .
- Expression:
- Ubiquitously expressed in all tissue examined.
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