Total DAPP1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4070C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • DAPP1
    • Human Swiss Prot No:
    • Q9UN19
    • Mouse Swiss Prot No:
    • Q9QXT1
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
    • Function:
    • protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process,dephosphorylation,
    • Subcellular Location:
    • Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
    • Expression:
    • Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.