Total CRMP2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4057C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • DPYSL2
    • Human Gene Id:
    • 1808
    • Human Swiss Prot No:
    • Q16555
    • Mouse Swiss Prot No:
    • O08553
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5 (By similarity). Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4.,tissue specificity:Ubiquitous.,
    • Subcellular Location:
    • Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Membrane . Tightly but non-covalently associated with membranes.
    • Expression:
    • Ubiquitous.