Total CDK1/CDC2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4036C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CDK1/CDK2/CDK3
    • Storage Stability:
    • 2-8°C/6 months
    • Detection Method:
    • Colorimetric
    • Function:
    • cell cycle checkpoint, DNA damage checkpoint, M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division,protein amino acid phosphorylation, proteolysis, ubiquitin-dependent protein catabolic process, phosphorus metabolic process, phosphate metabolic process, anti-apoptosis, response to DNA damage stimulus, cell cycle, mitosis, mitotic cell cycle checkpoint, mitotic cell cycle G2/M transition DNA damage checkpoint, intracellular signaling cascade,regulation of mitotic cell cycle, macromolecule catabolic process, proteasomal protein catabolic process, positive regulation of macromolecule metabolic process, regulation of cell death, phosphorylation, modification-dependent protein catabolic process, cell cycle process, cell cycle phase, protein catabolic process, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, regulation of p
    • Subcellular Location:
    • Nucleus. Cytoplasm. Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle. Cytoplasmic during the interphase. Colocalizes with SIRT2 on centrosome during prophase and on splindle fibers during metaphase of the mitotic cell cycle. Reversibly translocated from cytoplasm to nucleus when phosphorylated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
    • Expression:
    • Isoform 2 is found in breast cancer tissues.