Cleaved-MMP-15 (Y132) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3968C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • MMP15
    • Human Gene Id：
    • 4324
    • Human Swiss Prot No：
    • P51511
    • Mouse Swiss Prot No：
    • O54732
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2)
    • Detection Method：
    • Colorimetric
    • Background：
    • cofactor:Binds 1 zinc ion per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,tissue specificity:Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.,
    • Function：
    • proteolysis,
    • Subcellular Location：
    • Membrane ; Single-pass type I membrane protein ; Extracellular side .
    • Expression：
    • Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

    Attributes

    • Code：
    • KA3968C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-09
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