Cleaved-Cathepsin A 32k (R326) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3964C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • CTSA
    • Human Gene Id:
    • 5476
    • Human Swiss Prot No:
    • P10619
    • Mouse Swiss Prot No:
    • P16675
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain;Lysosomal protective protein 20 kDa chain]
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,
    • Function:
    • proteolysis, intracellular protein transport, protein localization, protein transport, cellular protein localization,establishment of protein localization, intracellular transport, cellular macromolecule localization,
    • Subcellular Location:
    • Lysosome.