Cleaved-Cathepsin A 32k (R326) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3964C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- CTSA
- Human Gene Id:
- 5476
- Human Swiss Prot No:
- P10619
- Mouse Swiss Prot No:
- P16675
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain;Lysosomal protective protein 20 kDa chain]
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,
- Function:
- proteolysis, intracellular protein transport, protein localization, protein transport, cellular protein localization,establishment of protein localization, intracellular transport, cellular macromolecule localization,
- Subcellular Location:
- Lysosome.
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