Cleaved-Cathepsin L1 HC (T288) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3942C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • CTSL1
    • Human Gene Id：
    • 1514
    • Human Swiss Prot No：
    • P07711
    • Mouse Swiss Prot No：
    • P06797
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Cathepsin L1 (EC 3.4.22.15) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain;Cathepsin L1 light chain]
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,
    • Function：
    • proteolysis,
    • Subcellular Location：
    • Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .

    Attributes

    • Code：
    • KA3942C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-05-07
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