Cleaved-Caspase-5 p10 (S331) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3938C
  • Applications:ELISA
  • Reactivity:Human;
    • Gene Name:
    • CASP5
    • Protein Name:
    • Caspase5
    • Human Gene Id:
    • 838
    • Human Swiss Prot No:
    • P51878
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Caspase-5 (CASP-5) (EC 3.4.22.58) (ICE(rel)-III) (Protease ICH-3) (Protease TY) [Cleaved into: Caspase-5 subunit p20;Caspase-5 subunit p10]
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.,function:Mediator of programmed cell death (apoptosis).,PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunits.,tissue specificity:Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.,
    • Function:
    • proteolysis, apoptosis, cell death, regulation of cell death, programmed cell death, death, regulation of apoptosis,regulation of programmed cell death,
    • Expression:
    • Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.