Cleaved-Spectrin α II (D1185) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3932C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • SPTAN1
    • Human Gene Id：
    • 6709
    • Human Swiss Prot No：
    • Q13813
    • Mouse Swiss Prot No：
    • P16546
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.,PTM:Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.,similarity:Belongs to the spectrin family.,similarity:Contains 1 SH3 domain.,similarity:Contains 23 spectrin repeats.,similarity:Contains 3 EF-hand domains.,subunit:Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1. Interacts with CALM.,
    • Function：
    • regulation of actin polymerization or depolymerization, negative regulation of organelle organization, regulation of actin filament length, regulation of actin filament polymerization, regulation of actin filament depolymerization,negative regulation of actin filament depolymerization, negative regulation of actin filament polymerization, negative regulation of protein complex assembly, regulation of protein polymerization, negative regulation of protein polymerization, regulation of cellular component size, regulation of actin cytoskeleton organization, regulation of actin filament-based process, regulation of organelle organization, negative regulation of protein complex disassembly,regulation of protein complex disassembly, regulation of protein complex assembly, regulation of cellular component biogenesis, negative regulation of cellular component organization, regulation of cytoskel
    • Subcellular Location：
    • Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. .

    Attributes

    • Code：
    • KA3932C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-01
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