• Gene Name：
• CYP4F2

• Human Gene Id：
• 8529

• Human Swiss Prot No：
• P78329

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• Leukotriene-B(4) omega-hydroxylase 1 (EC 1.14.13.30) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1)

• Detection Method：
• Colorimetric

• Background：
• catalytic activity:(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + O(2) = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP(+) + H(2)O.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver.,

• Function：
• fatty acid metabolic process, icosanoid metabolic process, leukotriene metabolic process, unsaturated fatty acid metabolic process, cellular alkene metabolic process, oxidation reduction,

• Subcellular Location：
• Microsome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein .

• Expression：
• Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).

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