• Gene Name：
• CYP39A1

• Human Gene Id：
• 51302

• Human Swiss Prot No：
• Q9NYL5

• Mouse Swiss Prot No：
• Q9JKJ9

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• 24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.13.99) (Cytochrome P450 39A1) (hCYP39A1) (Oxysterol 7-alpha-hydroxylase)

• Detection Method：
• Colorimetric

• Background：
• catalytic activity:(24R)-cholest-5-ene-3-beta,24-diol + NADPH + O(2) = (24R)-cholest-5-ene-3-beta,7-alpha,24-triol + NADP(+) + H(2)O.,cofactor:Heme group.,function:Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver specific.,

• Function：
• steroid biosynthetic process, bile acid biosynthetic process, steroid catabolic process, cholesterol catabolic process,digestion, steroid metabolic process, cholesterol metabolic process, bile acid metabolic process, lipid biosynthetic process, lipid catabolic process, organic acid biosynthetic process, organic acid catabolic process, sterol metabolic process, sterol catabolic process, bile acid catabolic process, carboxylic acid biosynthetic process, carboxylic acid catabolic process, oxidation reduction,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .

• Expression：
• Liver specific.

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