Total CYP2C8/9/18/19 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3888C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • CYP2C8/9/18/19
    • Storage Stability:
    • 2-8°C/6 months
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,caution:Alternative splicing has been shown to occur but the shorter forms are believed to be non-functional.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).,induction:By phenobarbital.,online information:CYP2C8 alleles,similarity:Belongs to the cytochrome P450 family.,
    • Function:
    • oxidation reduction,
    • Subcellular Location:
    • Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.