Total THC2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3861C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • MASTL
    • Human Swiss Prot No:
    • Q96GX5
    • Mouse Swiss Prot No:
    • Q8C0P0
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,disease:Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) [MIM:188000]. Thrombocytopenia is defined by a decrease in the number of platelets in circulating blood, resulting in the potential for increased bleeding and decreased ability for clotting.,function:Putative serine/threonine kinase which may be involved in megakaryocyte differentiation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
    • Subcellular Location:
    • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves to the cleavage furrow. .