Total TMEM16A Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3790C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- ANO1
- Human Gene Id:
- 55107
- Human Swiss Prot No:
- Q5XXA6
- Mouse Swiss Prot No:
- Q8BHY3
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2)
- Detection Method:
- Colorimetric
- Background:
- domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,
- Function:
- ion transport, anion transport, chloride transport, open tracheal system development, inorganic anion transport,respiratory system development,
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. .
- Expression:
- Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles.
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