Total WTAP Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3739C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • WTAP
    • Human Gene Id：
    • 9589
    • Human Swiss Prot No：
    • Q15007
    • Mouse Swiss Prot No：
    • Q9ER69
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. May be involved in mRNA splicing regulation.,induction:In smooth muscle cells, up-regulated after serum withdrawal, when cells become mature and non proliferative.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the fl(2)d family.,subunit:Interacts with WT1.,tissue specificity:Ubiquitously expressed.,
    • Function：
    • RNA processing, mRNA processing, cell cycle, RNA splicing, mRNA metabolic process,
    • Subcellular Location：
    • Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus. .
    • Expression：
    • Ubiquitously expressed.

    Attributes

    • Code：
    • KA3739C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-05-03
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