Total MB67 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3737C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • NR1I3
    • Human Gene Id:
    • 9970
    • Human Swiss Prot No:
    • Q14994
    • Mouse Swiss Prot No:
    • O35627
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
    • Detection Method:
    • Colorimetric
    • Background:
    • domain:Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.,function:Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.,induction:By dexamethasone.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer of NR1I3 and RXR. Interacts with PSMC4.,tissue specificity:Predominantly expressed in liver.,
    • Function:
    • transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
    • Subcellular Location:
    • Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7. .
    • Expression:
    • Predominantly expressed in liver.