Total Mi2-β Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3735C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • CHD4
    • Human Gene Id：
    • 1108
    • Human Swiss Prot No：
    • Q14839
    • Mouse Swiss Prot No：
    • Q6PDQ2
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:One of the main antigens reacting with anti-MI-2 positive sera of dermatomyositis.,function:Probable transcription regulator.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,similarity:Contains 2 PHD-type zinc fingers.,subunit:Central component of the nucleosome remodeling and histone deacetylase (NuRD) repressor complex. Interacts with TRIM27. Part of a complex containing ATR and HDAC2. Interacts with KLF1; the interaction depends on sumoylation of KLF1, and leads to its transcriptional repression.,
    • Function：
    • chromatin organization, chromatin assembly or disassembly, transcription, regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter, chromatin modification, regulation of transcription,regulation of RNA metabolic process, chromosome organization,
    • Subcellular Location：
    • Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with centrosomes in interphase. .

    Attributes

    • Code：
    • KA3735C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-02
    Order

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