Total GCKR Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3729C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- GCKR
- Human Gene Id:
- 2646
- Human Swiss Prot No:
- Q14397
- Mouse Swiss Prot No:
- Q91X44
- Rat Swiss Prot No:
- Q07071
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Glucokinase regulatory protein (Glucokinase regulator)
- Detection Method:
- Colorimetric
- Background:
- function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,
- Function:
- protein import into nucleus, translocation, cellular glucose homeostasis, protein targeting, protein import into nucleus,intracellular protein transport, nucleocytoplasmic transport, protein localization, protein transport, protein import,cellular homeostasis, protein localization in organelle, carbohydrate homeostasis, protein localization in nucleus,cellular protein localization, homeostatic process, glucose homeostasis, establishment of protein localization,intracellular transport, chemical homeostasis, nuclear transport, nuclear import, cellular chemical homeostasis, cellular macromolecule localization,
- Subcellular Location:
- Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
- Expression:
- Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
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