Total TLE4 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3680C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • TLE4
    • Human Gene Id:
    • 7091
    • Human Swiss Prot No:
    • Q04727
    • Mouse Swiss Prot No:
    • Q62441
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Transducin-like enhancer protein 4
    • Detection Method:
    • Colorimetric
    • Background:
    • caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,
    • Function:
    • transcription, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, regulation of transcription,
    • Subcellular Location:
    • Nucleus.
    • Expression:
    • In all tissues examined, mostly in brain, and muscle.