Total TLE4 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3680C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- TLE4
- Human Gene Id:
- 7091
- Human Swiss Prot No:
- Q04727
- Mouse Swiss Prot No:
- Q62441
- Rat Swiss Prot No:
- Q07141
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Transducin-like enhancer protein 4
- Detection Method:
- Colorimetric
- Background:
- caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,
- Function:
- transcription, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, regulation of transcription,
- Subcellular Location:
- Nucleus.
- Expression:
- In all tissues examined, mostly in brain, and muscle.
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