Total TFIIA-α Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3633C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • GTF2A1
    • Human Gene Id:
    • 2957
    • Human Swiss Prot No:
    • P52655
    • Mouse Swiss Prot No:
    • Q99PM3
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit);Transcription initiation factor IIA beta chain (TFIIA p19 subunit)]
    • Detection Method:
    • Colorimetric
    • Background:
    • function:TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.,PTM:The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteosomal degradation.,similarity:Belongs to the TFIIA subunit 1 family.,subunit:TFIIA is a heterodimer of the large unprocessed subunit 1 and a small subunit gamma. It was originally believed to be a heterotrimer of an alpha (p35), a beta (p19) and a gamma subunit (p12). TFIIA forms a complex with TBP.,
    • Function:
    • transcription, transcription, DNA-dependent, transcription initiation, RNA elongation, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, RNA elongation from RNA polymerase II promoter, protein complex assembly, general transcription from RNA polymerase II promoter, RNA biosynthetic process, macromolecular complex subunit organization, regulation of transcription, macromolecular complex assembly,protein complex biogenesis,
    • Subcellular Location:
    • Nucleus.