Total Casein Kinase Iα Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3615C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CSNK1A1
    • Human Gene Id:
    • 1452
    • Human Swiss Prot No:
    • P48729
    • Mouse Swiss Prot No:
    • Q8BK63
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, phosphorylation,
    • Subcellular Location:
    • Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Nucleus speckle . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). .