Total GATA-4 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3609C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • GATA4
    • Human Gene Id：
    • 2626
    • Human Swiss Prot No：
    • P43694
    • Mouse Swiss Prot No：
    • Q08369
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Transcription factor GATA-4 (GATA-binding factor 4)
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in GATA4 are the cause of atrial septal defect type 2 (ASD2) [MIM:607941]. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD2 patients show other heart abnormalities including ventricular and atrioventricular septal defects, pulmonary valve thickening or insufficiency of the cardiac valves. ASD2 is not associated with defects in the cardiac conduction system or non-cardiac abnormalities.,function:Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5.,similarity:Contains 2 GATA-type zinc fingers.,subunit:Interacts with ZNF260 (By similarity). Interacts with the homeobox domain of NKX2-5 through its C-terminal zinc finger. Also interacts with JARID2 which represses its ability to activate transcription of ANF. Interacts with NFATC4.,
    • Function：
    • in utero embryonic development, gastrulation with mouth forming second, regulation of cytokine production, positive regulation of cytokine production, heart looping, regionalization, heart morphogenesis, transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, cell-cell signaling, gastrulation, pattern specification process, ectodermal gut development, foregut morphogenesis, heart development, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of macromolecule biosynthetic process, regulation of vascular endothelial growth factor production, positive regulation vascular endothelial growth factor production, positive regulation of macromolecule m
    • Subcellular Location：
    • Nucleus .

    Attributes

    • Code：
    • KA3609C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-02
    Order

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