Total ERK 2 Cell-Based Colorimetric ELISA Kit_ImmunoWay Biotechnology Company |抗体|病理抗体|诊断抗体

Total ERK 2 Cell-Based Colorimetric ELISA Kit

Other Name：
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)

Function：
protein import into nucleus, translocation, MAPKKK cascade, nuclear translocation of MAPK, response to molecule of bacterial origin, activation of immune response, immune response-activating cell surface receptor signaling pathway,positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, pyrimidine base metabolic process, regulation of translation, protein amino acid phosphorylation, protein targeting, protein import into nucleus, phosphorus metabolic process, phosphate metabolic process, intracellular protein transport,nucleocytoplasmic transport, induction of apoptosis, chemotaxis, response to DNA damage stimulus, cell cycle, cell surface receptor linked signal transduction, intracellular signaling cascade, protein kinase cascade, small

Subcellular Location：
Cytoplasm, cytoskeleton, spindle . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm . Membrane, caveola . Cell junction, focal adhesion . Associated with the spindle during prometaphase and metaphase (By similarity). PEA15-binding and phosphorylated DAPK1 promote its cytoplasmic retention. Phosphorylation at Ser- 246 and Ser-248 as well as autophosphorylation at Thr-190 promote nuclear localization. .