Total SLC43A1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3484C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • SLC43A1
    • Human Gene Id:
    • 8501
    • Human Swiss Prot No:
    • O75387
    • Mouse Swiss Prot No:
    • Q8BSM7
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.,
    • Function:
    • amino acid transport, neutral amino acid transport, L-amino acid transport, amine transport, organic acid transport,carboxylic acid transport,
    • Subcellular Location:
    • Membrane ; Multi-pass membrane protein .
    • Expression:
    • In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.