Total Zic1/2/3 Cell-Based Colorimetric ELISA Kit_ImmunoWay Biotechnology Company |抗体|病理抗体|诊断抗体

Total Zic1/2/3 Cell-Based Colorimetric ELISA Kit

Background：
function:May play a role in cerebellar development.,similarity:Belongs to the GLI C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,tissue specificity:CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.,

Function：
pattern specification process, sensory organ development, behavior, regulation of smoothened signaling pathway, ear morphogenesis, inner ear morphogenesis, ear development, embryonic organ morphogenesis, embryonic organ development, embryonic morphogenesis, inner ear development,

Subcellular Location：
Nucleus. Cytoplasm . Localizes in the cytoplasm in presence of MDFIC overexpression. .

Expression：
CNS. A high level expression is seen in the cerebellum. Detected in the nuclei of the cerebellar granule cell lineage from the progenitor cells of the external germinal layer to the postmigrated cells of the internal granular layer. Detected in medulloblastoma (26/29 cases), but not present in all other tumors examined.