Total HBP1 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3472C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- HBP1
- Human Gene Id:
- 26959
- Human Swiss Prot No:
- O60381
- Mouse Swiss Prot No:
- Q8R316
- Rat Swiss Prot No:
- Q62661
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1)
- Detection Method:
- Colorimetric
- Background:
- function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,
- Function:
- transcription, cell cycle, cell cycle arrest, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, cell cycle process, regulation of transcription,
- Subcellular Location:
- Nucleus .
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