Total GSC2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3459C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • GSC2
    • Human Gene Id:
    • 2928
    • Human Swiss Prot No:
    • O15499
    • Mouse Swiss Prot No:
    • P56916
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Homeobox protein goosecoid-2 (GSC-2) (Homeobox protein goosecoid-like) (GSC-L)
    • Detection Method:
    • Colorimetric
    • Background:
    • developmental stage:Expressed in early human development as well as in a limited number of adult tissues.,disease:May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).,function:May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.,similarity:Belongs to the paired homeobox family. Bicoid subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Detected in adult testis and pituitary, and in 9-10 week fetal tissue (thorax). Probably expressed in other tissues at low levels.,
    • Function:
    • regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription, regulation of RNA metabolic process,
    • Subcellular Location:
    • Nucleus .
    • Expression:
    • Detected in adult testis and pituitary, and in 9-10 week fetal tissue (thorax). Probably expressed in other tissues at low levels.